MLB

St. Louis Cardinals vs Pittsburgh Pirates Prediction

Wed, Sep 23, 2026, 6:40 PM ET

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AccuScore's simulation makes Pittsburgh Pirates 59% to beat St. Louis Cardinals (41%). Projected score: St. Louis Cardinals 3.8, Pittsburgh Pirates 4.4.

Projection updated Sep 23, 8:00 AM ET

Who will win St. Louis Cardinals vs Pittsburgh Pirates?

AccuScore's simulation makes Pittsburgh Pirates the more likely winner at 59%. The projection updates as team news and prices move.

What is the predicted score for St. Louis Cardinals vs Pittsburgh Pirates?

AccuScore projects St. Louis Cardinals 3.8, Pittsburgh Pirates 4.4.