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← Today's Edges
NFL•Sun, Jan 10 • 12:00 AM
SF

San Francisco 49ers

6-1

VS
ARI

Arizona Cardinals

3-5

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NFL

San Francisco 49ers vs Arizona Cardinals Prediction, Odds & Live Score

Sat, Jan 9, 2027, 7:00 PM ET

Season outlook

San Francisco 49ers (6-1 so far) project to finish 12.6–4.4 and make the playoffs in 92% of AccuScore's simulated seasons.

Arizona Cardinals (3-5 so far) project to finish 6.9–10.1 and make the playoffs in 8% of AccuScore's simulated seasons.

TeamProjected recordDivision titlePlayoffs
San Francisco 49ers12.6–4.475%92%
Arizona Cardinals6.9–10.11%8%

From AccuScore's daily simulation of the rest of the season. Every NFL team's projection →

Form, head-to-head and betting trends

How San Francisco 49ers and Arizona Cardinals come into this game: their latest results, every meeting on record and how each has fared against the betting market.

Recent form

San Francisco 49ersLWWWW
  • Oct 25at Atlanta FalconsL 20–29
  • Oct 19vs Washington CommandersW 23–17
  • Oct 11at Seattle SeahawksW 32–29
  • Oct 4vs Denver BroncosW 24–14
  • Sep 27vs Arizona CardinalsW 36–30

San Francisco 49ers have won 4 of their last 5 (L-W-W-W-W, most recent first).

Arizona CardinalsWLWLL
  • Nov 1at Dallas CowboysW 33–30
  • Oct 25vs Denver BroncosL 16–30
  • Oct 18at Los Angeles RamsW 18–16
  • Oct 11vs Detroit LionsL 21–45
  • Oct 4at New York GiantsL 24–36

Arizona Cardinals have won 2 of their last 5 (W-L-W-L-L, most recent first).

Head-to-head

The teams have met 31 times since 2011: San Francisco 49ers 16, Arizona Cardinals 15. The last meeting, on Sep 27, 2026, finished Arizona Cardinals 30, San Francisco 49ers 36.

  • Sep 27, 2026ARI 30 – 36 SF
  • Nov 16, 2025SF 41 – 22 ARI
  • Sep 21, 2025ARI 15 – 16 SF
  • Jan 5, 2025SF 24 – 47 ARI
  • Oct 6, 2024ARI 24 – 23 SF
Every San Francisco 49ers vs Arizona Cardinals meeting →

Betting trends

San Francisco 49ers are 115-52-1 as favourite and 36-69 as underdog, and 73-64 on the road (53% of 137 games, 2011–2026).

Arizona Cardinals are 57-36-1 as favourite and 55-104-1 as underdog, and 60-64-2 at home (48% of 126 games, 2011–2026).

RecordSFARI
As favourite115-52-157-36-1
As underdog36-6955-104-1
At home79-57-160-64-2
On the road73-6453-78

Straight-up records from AccuScore's game archive. Favourite and underdog are the market's, decided by the point spread. How the NFL odds have moved →