San Francisco 49ers vs Arizona Cardinals Prediction

1 meeting scheduled · 31 played since 2011

Next game · Sat, Jan 9, 7:00 PM ET

San Francisco 49ers

Arizona Cardinals

AccuScore's projection is posted closer to the game.Full breakdown and odds →

Simulation stories: San Francisco 49ers and Arizona Cardinals

Nov 5
49ers' Super Bowl Talk: AccuScore Puts Them at 90.7% to Make the Playoffs
San Francisco 49ers sit at 6-1 with a 90.7% playoff probability in AccuScore's simulation as DeForest Buckner's return stirs Super Bowl talk.
Nov 3
Cardinals' Switch to Gardner Minshew: Playoff Odds Slip From 5.9% to 4%
AccuScore simulated the rest of the Arizona Cardinals' season 50,000 times with each quarterback starting, and the numbers favor keeping Jacoby Brissett.

Past meetings · SF 16–15 ARI

DateFinalAccuScoreFavourite

Sep 27, 2026ARI 30 – 36 SFSF 77%✓ won

Nov 16, 2025SF 41 – 22 ARISF 65%✓ won

Sep 21, 2025ARI 15 – 16 SFARI 52%✗ lost

Jan 5, 2025SF 24 – 47 ARIARI 64%✓ won

Oct 6, 2024ARI 24 – 23 SFSF 78%✗ lost

Show 26 more

DateFinalAccuScoreFavourite

Dec 17, 2023SF 45 – 29 ARISF 85%✓ won

Oct 1, 2023

When do San Francisco 49ers and Arizona Cardinals play next?

San Francisco 49ers visit Arizona Cardinals on Sat, Jan 9, 7:00 PM ET.

Who won the last San Francisco 49ers vs Arizona Cardinals game?

On Sep 27, 2026 it finished Arizona Cardinals 30, San Francisco 49ers 36.

What is the San Francisco 49ers vs Arizona Cardinals head-to-head record?

Since 2011: San Francisco 49ers 16 wins, Arizona Cardinals 15 over 31 meetings on record.

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Jan 8, 2023ARI 13 – 38 SFSF 91%✓ won

Nov 21, 2022SF 38 – 10 ARISF 77%✓ won

Nov 7, 2021ARI 31 – 17 SFSF 64%✗ lost

Oct 10, 2021SF 10 – 17 ARIARI 70%✓ won

Dec 26, 2020SF 20 – 12 ARIARI 71%✗ lost

Sep 13, 2020ARI 24 – 20 SFSF 66%✗ lost

Nov 17, 2019ARI 26 – 36 SFSF 73%✓ won

Oct 31, 2019SF 28 – 25 ARISF 65%✓ won

Oct 28, 2018SF 15 – 18 ARIARI 51%✓ won

Oct 7, 2018ARI 28 – 18 SFSF 61%✗ lost

Nov 5, 2017ARI 20 – 10 SFARI 52%✓ won

Oct 1, 2017SF 15 – 18 ARIARI 77%✓ won

Nov 13, 2016SF 20 – 23 ARIARI 85%✓ won

Oct 9, 2016ARI 33 – 21 SFARI 68%✓ won

Nov 29, 2015ARI 19 – 13 SFARI 75%✓ won

Sep 27, 2015SF 7 – 47 ARIARI 65%✓ won

Dec 28, 2014ARI 17 – 20 SFSF 75%✓ won

Sep 21, 2014SF 14 – 23 ARISF 50%✗ lost

Dec 29, 2013SF 23 – 20 ARISF 59%✓ won

Oct 13, 2013ARI 20 – 32 SFSF 83%✓ won

Dec 30, 2012ARI 13 – 27 SFSF 86%✓ won

Oct 29, 2012SF 24 – 3 ARISF 70%✓ won

Dec 11, 2011SF 19 – 21 ARISF 61%✗ lost

Nov 20, 2011ARI 7 – 23 SFSF 80%✓ won

AccuScore's most likely outcome came in 23 of the 31 meetings it priced.

Meetings from 2011 on include AccuScore's game archive.

Season outlook

San Francisco 49ers (6-1 so far) project to finish 12.6–4.4 and make the playoffs in 92% of AccuScore's simulated seasons.

Arizona Cardinals (3-5 so far) project to finish 6.9–10.1 and make the playoffs in 8% of AccuScore's simulated seasons.

Team	Projected record	Division title	Playoffs
San Francisco 49ers	12.6–4.4	75%	92%
Arizona Cardinals	6.9–10.1	1%	8%

From AccuScore's daily simulation of the rest of the season. Every NFL team's projection →